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However, the detail role of miR has not been fully elucidated in breast cancer. In this study, we aimed to investigate the biological role and molecular mechanisms of miR in drug resistance in breast cancer cell lines and in xenograft model. We show that miR is decreased in human breast cancer specimens and in paclitaxel-resistant PR cells. Taken together, our findings suggested that miR might be considered as important and potential target in paclitaxel-resistant breast cancer treatment.
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Jessica Wongso laughs when asked if she laced Mirna Salihin's coffee with cyanide

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Involvement of miR in resistance to paclitaxel by regulating YWHAZ in breast cancer

Share this article Share Sandy also said: Wayan Mirna Salihin pictured died on January 6 after sipping a Vietnamese iced coffee ordered by Ms Wongso Wongso flashes a 'thumbs up' after appearing in front of media Mirna Salihin's sister Sandy said she believed Wongso was enjoying the attention of the trial and called for a 'life for a life' Murder accused Jessica Wongso has denied the charges against her Prosecutors allege Wongso sought to 'avenge her pain' over a break-up with her Australian boyfriend Patrick O'Connor, whom Ms Salihin did not approve of. Her alleged crime was described by prosecutors in the Central Jakarta District Court last week as 'cruel' and 'sadistic'. During the marathon hearing, prosecutors did not give a definitive answer as to where Wongso obtained the cyanide that allegedly killed her friend, arguing instead that it was 'easily available on the black market' While the charge of premeditated murder in Indonesia carries the maximum penalty of death, the Australian Federal Police only agreed to assist the investigation on the proviso such a sentence would not be sought or imposed. However, judges feel they aren't bound by the agreement according to reports.
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Involvement of miR-451 in resistance to paclitaxel by regulating YWHAZ in breast cancer

While its role and mechanism participated in NPC progression are still little known. Here, we explored the effect of miR on the progression of NPC. Results demonstrated that miR was markedly down-regulated in NPC tissues and cell lines. Electronic supplementary material The online version of this article doi:
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Received Mar 30; Accepted Oct 6. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This article has been cited by other articles in PMC. MiR has been implicated in several types of cancer regulation; however, relatively little is known about miR in human HCC. In the present study, we showed that the overexpression of miR accelerates the tumor progression of HCC in vitro and in vivo through its new target gene, CPEB3.
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